Exploring sequence characteristics related to high-level production of secreted proteins in Aspergillus niger.

Protein sequence features are explored in relation to the production of over-expressed extracellular proteins by fungi. Knowledge on features influencing protein production and secretion could be employed to improve enzyme production levels in industrial bioprocesses via protein engineering. A large...

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Bibliographic Details
Main Authors: Bastiaan A van den Berg, Marcel J T Reinders, Marc Hulsman, Liang Wu, Herman J Pel, Johannes A Roubos, Dick de Ridder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462195?pdf=render