ASCOT identifies key regulators of neuronal subtype-specific splicing

The increasing amount of raw RNA-seq data calls for new computational methods to mine information. Here, the authors present ASCOT, a computational resource to identify splice variants in RNA-seq data, and apply it to splicing patterns in neurons and unique splicing patterns in rod photoreceptors.

Bibliographic Details
Main Authors: Jonathan P. Ling, Christopher Wilks, Rone Charles, Patrick J. Leavey, Devlina Ghosh, Lizhi Jiang, Clayton P. Santiago, Bo Pang, Anand Venkataraman, Brian S. Clark, Abhinav Nellore, Ben Langmead, Seth Blackshaw
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-14020-5