miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis.

miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis.

Antiviral responses must rapidly defend against infection while minimizing inflammatory damage, but the mechanisms that regulate the magnitude of response within an infected cell are not well understood. miRNAs are small non-coding RNAs that suppress protein levels by binding target sequences on the...

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Bibliographic Details
Main Authors: Carrie M Rosenberger, Rebecca L Podyminogin, Alan H Diercks, Piper M Treuting, Jacques J Peschon, David Rodriguez, Madhumati Gundapuneni, Mitchell J Weiss, Alan Aderem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5393898?pdf=render

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http://europepmc.org/articles/PMC5393898?pdf=render

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