Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation.

by Peter S Askovich, Stephen A Ramsey, Alan H Diercks, Kathleen A Kennedy, Theo A Knijnenburg, Alan Aderem
Published 2017-01-01

Bright field microscopy as an alternative to whole cell fluorescence in automated analysis of macrophage images.

by Jyrki Selinummi, Pekka Ruusuvuori, Irina Podolsky, Adrian Ozinsky, Elizabeth Gold, Olli Yli-Harja, Alan Aderem, Ilya Shmulevich
Published 2009-10-01

Control of parasitophorous vacuole expansion by LYST/Beige restricts the intracellular growth of Leishmania amazonensis.

by Jude Wilson, Chau Huynh, Kathleen A Kennedy, Diane M Ward, Jerry Kaplan, Alan Aderem, Norma W Andrews
Published 2008-10-01

Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.

by Stephen A Ramsey, Yuliya Vengrenyuk, Prashanthi Menon, Irina Podolsky, Jonathan E Feig, Alan Aderem, Edward A Fisher, Elizabeth S Gold
Published 2014-12-01

miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis.

by Carrie M Rosenberger, Rebecca L Podyminogin, Alan H Diercks, Piper M Treuting, Jacques J Peschon, David Rodriguez, Madhumati Gundapuneni, Mitchell J Weiss, Alan Aderem
Published 2017-04-01

Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.

by Thomas R Hawn, Delia Scholes, Hongwei Wang, Sue S Li, Ann E Stapleton, Marta Janer, Alan Aderem, Walter E Stamm, Lue Ping Zhao, Thomas M Hooton
Published 2009-12-01

Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses.

by Peter S Askovich, Catherine J Sanders, Carrie M Rosenberger, Alan H Diercks, Pradyot Dash, Garnet Navarro, Peter Vogel, Peter C Doherty, Paul G Thomas, Alan Aderem
Published 2013-01-01

The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.

by Paul L Bollyky, Jeffrey B Bice, Ian R Sweet, Ben A Falk, John A Gebe, April E Clark, Vivian H Gersuk, Alan Aderem, Thomas R Hawn, Gerald T Nepom
Published 2009-01-01

Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.

by Thomas R Hawn, Delia Scholes, Shuying S Li, Hongwei Wang, Yin Yang, Pacita L Roberts, Ann E Stapleton, Marta Janer, Alan Aderem, Walter E Stamm, Lue Ping Zhao, Thomas M Hooton
Published 2009-06-01

Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection.

by Johannes Nemeth, Gregory S Olson, Alissa C Rothchild, Ana N Jahn, Dat Mai, Fergal J Duffy, Jared L Delahaye, Sanjay Srivatsan, Courtney R Plumlee, Kevin B Urdahl, Elizabeth S Gold, Alan Aderem, Alan H Diercks
Published 2020-07-01

A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

by Jarrod S. Johnson, Nicholas De Veaux, Alexander W. Rives, Xavier Lahaye, Sasha Y. Lucas, Brieuc P. Perot, Marine Luka, Victor Garcia-Paredes, Lynn M. Amon, Aaron Watters, Ghaith Abdessalem, Alan Aderem, Nicolas Manel, Dan R. Littman, Richard Bonneau, Mickaël M. Ménager
Published 2020-01-01

Correction: Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.

by Stephen A. Ramsey, Sandy L. Klemm, Daniel E. Zak, Kathleen A. Kennedy, Vesteinn Thorsson, Bin Li, Mark Gilchrist, Elizabeth S. Gold, Carrie D. Johnson, Vladimir Litvak, Garnet Navarro, Jared C. Roach, Carrie M. Rosenberger, Alistair G. Rust, Natalya Yudkovsky, Alan Aderem, Ilya Shmulevich
Published 2008-03-01

Correction: Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.

by Stephen A. Ramsey, Sandy L. Klemm, Daniel E. Zak, Kathleen A. Kennedy, Vesteinn Thorsson, Bin Li, Mark Gilchrist, Elizabeth S. Gold, Carrie D. Johnson, Vladimir Litvak, Garnet Navarro, Jared C. Roach, Carrie M. Rosenberger, Alistair G. Rust, Natalya Yudkovsky, Alan Aderem, Ilya Shmulevich
Published 2008-04-01

Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics.

by Stephen A Ramsey, Sandy L Klemm, Daniel E Zak, Kathleen A Kennedy, Vesteinn Thorsson, Bin Li, Mark Gilchrist, Elizabeth S Gold, Carrie D Johnson, Vladimir Litvak, Garnet Navarro, Jared C Roach, Carrie M Rosenberger, Alistair G Rust, Natalya Yudkovsky, Alan Aderem, Ilya Shmulevich
Published 2008-03-01

Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.

by Nguyen Thuy Thuong Thuong, Sarah J Dunstan, Tran Thi Hong Chau, Vesteinn Thorsson, Cameron P Simmons, Nguyen Than Ha Quyen, Guy E Thwaites, Nguyen Thi Ngoc Lan, Martin Hibberd, Yik Y Teo, Mark Seielstad, Alan Aderem, Jeremy J Farrar, Thomas R Hawn
Published 2008-12-01

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

by Ying Du, Ethan G. Thompson, Julius Muller, Joseph Valvo, Jackie Braun, Smitha Shankar, Robert A. van den Berg, Erik Jongert, Drew Dover, Jerald Sadoff, Jenny Hendriks, Malcolm J. Gardner, W. Ripley Ballou, Jason A. Regules, Robbert van der Most, Alan Aderem, Christian F. Ockenhouse, Adrian V. Hill, Ulrike Wille-Reece, Daniel E. Zak
Published 2020-04-01

Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.

by Thomas J Scriba, Adam Penn-Nicholson, Smitha Shankar, Tom Hraha, Ethan G Thompson, David Sterling, Elisa Nemes, Fatoumatta Darboe, Sara Suliman, Lynn M Amon, Hassan Mahomed, Mzwandile Erasmus, Wendy Whatney, John L Johnson, W Henry Boom, Mark Hatherill, Joe Valvo, Mary Ann De Groote, Urs A Ochsner, Alan Aderem, Willem A Hanekom, Daniel E Zak, other members of the ACS cohort study team
Published 2017-11-01

Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial

by Daniel F. Hoft, Azra Blazevic, Asmir Selimovic, Aldin Turan, Jan Tennant, Getahun Abate, John Fulkerson, Daniel E. Zak, Robert Walker, Bruce McClain, Jerry Sadoff, Judy Scott, Barbara Shepherd, Jasur Ishmukhamedov, David A. Hokey, Veerabadran Dheenadhayalan, Smitha Shankar, Lynn Amon, Garnet Navarro, Rebecca Podyminogin, Alan Aderem, Lew Barker, Michael Brennan, Robert S. Wallis, Anne A. Gershon, Michael D. Gershon, Sharon Steinberg
Published 2016-05-01