Ythdf2-mediated m6A mRNA clearance modulates neural development in mice

Ythdf2-mediated m6A mRNA clearance modulates neural development in mice

Abstract Background N 6 -methyladenosine (m6A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of this mark is required for the temporal control of...

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Bibliographic Details
Main Authors: Miaomiao Li, Xu Zhao, Wei Wang, Hailing Shi, Qingfei Pan, Zhike Lu, Sonia Peña Perez, Rajikala Suganthan, Chuan He, Magnar Bjørås, Arne Klungland
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Genome Biology
Subjects:
Ythdf2
N 6 -methyladenosine (m6A)
Neural development
Neurogenesis
mRNA clearance
Online Access:http://link.springer.com/article/10.1186/s13059-018-1436-y

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http://link.springer.com/article/10.1186/s13059-018-1436-y

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