Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis

Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis

Gut microbiota dysbiosis has been implicated in MS and other immune diseases, although it remains unclear how manipulating the gut microbiota may affect the disease course. Using a well-established model of progressive MS triggered by intracranial infection with Theiler's murine encephalomyelit...

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Bibliographic Details
Main Authors: Leyre Mestre, Francisco Javier Carrillo-Salinas, Miriam Mecha, Ana Feliú, Carmen Espejo, José Carlos Álvarez-Cermeño, Luisa María Villar, Carmen Guaza
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
Theiler's virus model
gut microbiota
Treg and Breg cells
neuroinflammation
multiple sclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01374/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01374/full

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