Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes

Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes

Abstract Apples are well known to have various benefits for the human body. Procyanidins are a class of polyphenols found in apples that have demonstrated effects on the circulatory system and skeletal organs. Osteoarthritis (OA) is a locomotive syndrome that is histologically characterized by carti...

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Bibliographic Details
Main Authors: Isao Masuda, Masato Koike, Shohei Nakashima, Yu Mizutani, Yusuke Ozawa, Kenji Watanabe, Yoko Sawada, Hiroshi Sugiyama, Atsushi Sugimoto, Hidetoshi Nojiri, Koichi Sashihara, Koutaro Yokote, Takahiko Shimizu
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25348-1

Internet

https://doi.org/10.1038/s41598-018-25348-1

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