Extracellular Disposal of Tumor-Suppressor miRs-145 and -34a via Microvesicles and 5-FU Resistance of Human Colon Cancer Cells

Extracellular Disposal of Tumor-Suppressor miRs-145 and -34a via Microvesicles and 5-FU Resistance of Human Colon Cancer Cells

The dysregulation of microRNA (miRNA) expression causes various kinds of diseases. Especially, alterations in miRNA expression levels are frequently observed in human tumor cells and are associated with cancer pathogenesis. Earlier we established Fluorouracil (5-FU)-resistant human colon cancer DLD-...

Full description

Bibliographic Details
Main Authors: Yukihiro Akao, Fiona Khoo, Minami Kumazaki, Haruka Shinohara, Kohei Miki, Nami Yamada
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:International Journal of Molecular Sciences
Subjects:
miR-34a
miR-145
5-FU
microvesicles
drug resistance
Online Access:http://www.mdpi.com/1422-0067/15/1/1392

Internet

http://www.mdpi.com/1422-0067/15/1/1392

Similar Items