Structural basis for transcription complex disruption by the Mfd translocase

Structural basis for transcription complex disruption by the Mfd translocase

Transcription-coupled repair (TCR) is a sub-pathway of nucleotide excision repair (NER) that preferentially removes lesions from the template-strand (t-strand) that stall RNA polymerase (RNAP) elongation complexes (ECs). Mfd mediates TCR in bacteria by removing the stalled RNAP concealing the lesion...

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Bibliographic Details
Main Authors: Jin Young Kang, Eliza Llewellyn, James Chen, Paul Dominic B Olinares, Joshua Brewer, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
cryo-electron microscopy
Mfd
RNA polymerase
transcription-coupled repair
transcription repair coupling factor
Online Access:https://elifesciences.org/articles/62117

Internet

https://elifesciences.org/articles/62117

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