A Bioinformatics Model of Human Diseases on the Basis of Differentially Expressed Genes (of Domestic versus Wild Animals) That Are Orthologs of Human Genes Associated with Reproductive-Potential Changes

A Bioinformatics Model of Human Diseases on the Basis of Differentially Expressed Genes (of Domestic versus Wild Animals) That Are Orthologs of Human Genes Associated with Reproductive-Potential Changes

Earlier, after our bioinformatic analysis of single-nucleotide polymorphisms of TATA-binding protein-binding sites within gene promoters on the human Y chromosome, we suggested that human reproductive potential diminishes during self-domestication. Here, we implemented bioinformatics models of human...

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Bibliographic Details
Main Authors: Gennady Vasiliev, Irina Chadaeva, Dmitry Rasskazov, Petr Ponomarenko, Ekaterina Sharypova, Irina Drachkova, Anton Bogomolov, Ludmila Savinkova, Mikhail Ponomarenko, Nikolay Kolchanov, Alexander Osadchuk, Dmitry Oshchepkov, Ludmila Osadchuk
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
reproductive potential
animal model of human disease
domestication
in vivo verification
RNA-seq
differentially expressed gene
Online Access:https://www.mdpi.com/1422-0067/22/5/2346

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https://www.mdpi.com/1422-0067/22/5/2346

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