Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development.

Muscle contractile proteins are expressed as a series of developmental isoforms that are in constant dynamic remodeling during embryogenesis, but how obsolete molecules are recognized and removed is not known. Ozz is a developmentally regulated protein that functions as the adaptor component of a RI...

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Bibliographic Details
Main Authors: Yvan Campos, Xiaohui Qiu, Edmar Zanoteli, Simon Moshiach, Naja Vergani, Antonella Bongiovanni, A John Harris, Alessandra d'Azzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2844429?pdf=render