Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

In humans, clearance of hepatitis C virus (HCV) infection is associated with genetic variation near the IL-28B gene and the induction of interferon-stimulated genes, like IP-10. Also in chimpanzees spontaneous clearance of HCV is observed. To study whether similar correlations exist in these animals...

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Main Authors: Babs E Verstrepen, Natasja G de Groot, Zwier M A Groothuismink, Ernst J Verschoor, Rik A de Groen, Willy M Bogers, Harry L A Janssen, Petra Mooij, Ronald E Bontrop, Gerrit Koopman, Andre Boonstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3484116?pdf=render