The Crosstalk of Endoplasmic Reticulum (ER) Stress Pathways with NF-κB: Complex Mechanisms Relevant for Cancer, Inflammation and Infection

The Crosstalk of Endoplasmic Reticulum (ER) Stress Pathways with NF-κB: Complex Mechanisms Relevant for Cancer, Inflammation and Infection

Stressful conditions occuring during cancer, inflammation or infection activate adaptive responses that are controlled by the unfolded protein response (UPR) and the nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-κB) signaling pathway. These systems can be triggered...

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Bibliographic Details
Main Authors: M. Lienhard Schmitz, M. Samer Shaban, B. Vincent Albert, Anke Gökçen, Michael Kracht
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Biomedicines
Subjects:
ER stress
cancer
infection
inflammation
unfolded protein response
NF-κB
IκBα
thapsigargin
Online Access:http://www.mdpi.com/2227-9059/6/2/58

Internet

http://www.mdpi.com/2227-9059/6/2/58

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