Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Abstract Background Hansen’s disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins and past dissemination patterns are...

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Main Authors: Saskia Pfrengle, Judith Neukamm, Meriam Guellil, Marcel Keller, Martyna Molak, Charlotte Avanzi, Alena Kushniarevich, Núria Montes, Gunnar U. Neumann, Ella Reiter, Rezeda I. Tukhbatova, Nataliya Y. Berezina, Alexandra P. Buzhilova, Dmitry S. Korobov, Stian Suppersberger Hamre, Vitor M. J. Matos, Maria T. Ferreira, Laura González-Garrido, Sofia N. Wasterlain, Célia Lopes, Ana Luisa Santos, Nathalie Antunes-Ferreira, Vitória Duarte, Ana Maria Silva, Linda Melo, Natasa Sarkic, Lehti Saag, Kristiina Tambets, Philippe Busso, Stewart T. Cole, Alexei Avlasovich, Charlotte A. Roberts, Alison Sheridan, Craig Cessford, John Robb, Johannes Krause, Christiana L. Scheib, Sarah A. Inskip, Verena J. Schuenemann
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Biology
Subjects:
Ancient DNA
Ancient pathogen genomics
Mycobacterium leprae
Pathogen diversity
Leprosaria
Pathogen population dynamics
Online Access:https://doi.org/10.1186/s12915-021-01120-2

Internet

https://doi.org/10.1186/s12915-021-01120-2

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