GAD2 on chromosome 10p12 is a candidate gene for human obesity.

GAD2 on chromosome 10p12 is a candidate gene for human obesity.

The gene GAD2 encoding the glutamic acid decarboxylase enzyme (GAD65) is a positional candidate gene for obesity on Chromosome 10p11-12, a susceptibility locus for morbid obesity in four independent ethnic populations. GAD65 catalyzes the formation of gamma-aminobutyric acid (GABA), which interacts...

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Bibliographic Details
Main Authors: Philippe Boutin, Christian Dina, Francis Vasseur, Séverine Dubois, Laetitia Corset, Karin Séron, Lynn Bekris, Janice Cabellon, Bernadette Neve, Valérie Vasseur-Delannoy, Mohamed Chikri, M Aline Charles, Karine Clement, Ake Lernmark, Philippe Froguel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2003-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0000068

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https://doi.org/10.1371/journal.pbio.0000068

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