A novel stochastic simulation approach enables exploration of mechanisms for regulating polarity site movement.

Cells polarize their movement or growth toward external directional cues in many different contexts. For example, budding yeast cells grow toward potential mating partners in response to pheromone gradients. Directed growth is controlled by polarity factors that assemble into clusters at the cell me...

Full description

Bibliographic Details
Main Authors: Samuel A Ramirez, Michael Pablo, Sean Burk, Daniel J Lew, Timothy C Elston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008525