DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells

DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells

The human DEAD/H-box RNA helicase DDX6 (RCK/p54) is a protein encoded by the fusion gene from the t(11;14)(q23;q32) chromosomal translocation observed in human B-cell lymphoma cell line RC-K8. DDX6 has a variety of functions such as translation initiation, pre-mRNA splicing, and ribosome assembly. H...

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Bibliographic Details
Main Authors: Toshihiro Tajirika, Yoshihisa Tokumaru, Kohei Taniguchi, Nobuhiko Sugito, Nobuhisa Matsuhashi, Manabu Futamura, Kazuyoshi Yanagihara, Yukihiro Akao, Kazuhiro Yoshida
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
RNA-helicase DDX6
FGFR2
HER2
gastric cancer
Online Access:http://www.mdpi.com/1422-0067/19/7/2005

Internet

http://www.mdpi.com/1422-0067/19/7/2005

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