Reversal of carbapenem-resistance in Shewanella algae by CRISPR/Cas9 genome editing

Antibiotic resistance in pathogens is a growing threat to human health. Of particular concern is resistance to carbapenem, which is an antimicrobial agent listed as critically important by the World Health Organization. With the global spread of carbapenem-resistant organisms, there is an urgent nee...

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Bibliographic Details
Main Authors: Zong-Yen Wu, Yao-Ting Huang, Wen-Cheng Chao, Shu-Peng Ho, Jan-Fang Cheng, Po-Yu Liu
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123219300104