The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson’s disease

Abstract Parkinson’s disease (PD) is associated with neuronal damage in the brain and gut. This work compares changes in the enteric nervous system (ENS) of commonly used mouse models of PD that exhibit central neuropathy and a gut phenotype. Enteric neuropathy was assessed in five mouse models: per...

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Bibliographic Details
Main Authors: Rachel M. McQuade, Lewis M. Singleton, Hongyi Wu, Sophie Lee, Remy Constable, Madeleine Di Natale, Mitchell T. Ringuet, Joel P. Berger, Jessica Kauhausen, Clare L. Parish, David I. Finkelstein, John B. Furness, Shanti Diwakarla
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86917-5