Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

Abstract Background MicroRNAs (miRNAs) have been reported as deregulated in active brain lesions derived from patients with multiple sclerosis (MS). In there, these post-transcriptional regulators may elicit very important effects but proper identification of miRNA candidates as potential biomarkers...

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Bibliographic Details
Main Authors: María Muñoz-San Martín, Gemma Reverter, Rene Robles-Cedeño, Maria Buxò, Francisco José Ortega, Imma Gómez, Jordi Tomàs-Roig, Naiara Celarain, Luisa María Villar, Hector Perkal, José Manuel Fernández-Real, Ester Quintana, Lluís Ramió-Torrentà
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Active lesions
Epigenetics
Gadolinium positive (Gd+)
Inflammation
miRNAs
Multiple sclerosis
Online Access:http://link.springer.com/article/10.1186/s12974-019-1590-5

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http://link.springer.com/article/10.1186/s12974-019-1590-5

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