Biophysical and computational methods to analyze amino acid interaction networks in proteins

Globular proteins are held together by interacting networks of amino acid residues. A number of different structural and computational methods have been developed to interrogate these amino acid networks. In this review, we describe some of these methods, including analyses of X-ray crystallographic...

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Bibliographic Details
Main Authors: Kathleen F. O'Rourke, Scott D. Gorman, David D. Boehr
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
NMR
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037016300216