Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus.

Although human immunodeficiency type 1 (HIV-1) infection induces strong antibody responses to the viral envelope glycoprotein (Env) only a few of these antibodies possess the capacity to neutralize a broad range of strains. The induction of such antibodies represents an important goal in the develop...

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Main Authors: Donatien Kamdem Toukam, Matthias Tenbusch, Alexander Stang, Vladimir Temchura, Michael Storcksdieck Genannt Bonsmann, Bastian Grewe, Stefanie Koch, Andreas Meyerhans, Godwin Nchinda, Lazare Kaptue, Klaus Uberla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364164?pdf=render