Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors

by Nadine Bongard, Dennis Lapuente, Sonja Windmann, Ulf Dittmer, Matthias Tenbusch, Wibke Bayer
Published 2017-04-01

Modulation of Vaccine-Induced HIV-1-Specific Immune Responses by Co-Electroporation of PD-L1 Encoding DNA

by Pierre Tannig, Antonia Sophia Peter, Dennis Lapuente, Stephan Klessing, Dominik Damm, Matthias Tenbusch, Klaus Überla, Vladimir Temchura
Published 2020-01-01

Innate signalling molecules as genetic adjuvants do not alter the efficacy of a DNA-based influenza A vaccine.

by Dennis Lapuente, Viktoria Stab, Michael Storcksdieck Genannt Bonsmann, Andre Maaske, Mario Köster, Han Xiao, Christina Ehrhardt, Matthias Tenbusch
Published 2020-01-01

Genetic Co-Administration of Soluble PD-1 Ectodomains Modifies Immune Responses against Influenza A Virus Induced by DNA Vaccination

by Pierre Tannig, Antonia Sophia Peter, Dennis Lapuente, Stephan Klessing, Anna Schmidt, Dominik Damm, Matthias Tenbusch, Klaus Überla, Vladimir Temchura
Published 2020-10-01

Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination

by Rebecca Heß, Michael Storcksdieck genannt Bonsmann, Dennis Lapuente, Andre Maaske, Carsten Kirschning, Jürgen Ruland, Bernd Lepenies, Drew Hannaman, Matthias Tenbusch, Klaus Überla
Published 2019-02-01

A DNA Vaccine Encoding the Gn Ectodomain of Rift Valley Fever Virus Protects Mice via a Humoral Response Decreased by DEC205 Targeting

by Tiphany Chrun, Tiphany Chrun, Sandra Lacôte, Céline Urien, Charles-Adrien Richard, Matthias Tenbusch, Nicolas Aubrey, Coralie Pulido, Latifa Lakhdar, Philippe Marianneau, Isabelle Schwartz-Cornil
Published 2019-04-01

Protective efficacy and immunogenicity of a combinatory DNA vaccine against Influenza A Virus and the Respiratory Syncytial Virus.

by Viktoria Stab, Sandra Nitsche, Thomas Niezold, Michael Storcksdieck Genannt Bonsmann, Andrea Wiechers, Bettina Tippler, Drew Hannaman, Christina Ehrhardt, Klaus Uberla, Thomas Grunwald, Matthias Tenbusch
Published 2013-01-01

Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus.

by Donatien Kamdem Toukam, Matthias Tenbusch, Alexander Stang, Vladimir Temchura, Michael Storcksdieck Genannt Bonsmann, Bastian Grewe, Stefanie Koch, Andreas Meyerhans, Godwin Nchinda, Lazare Kaptue, Klaus Uberla
Published 2012-01-01

Forced expiration measurements in mouse models of obstructive and restrictive lung diseases

by Fien C. Devos, André Maaske, Annette Robichaud, Lore Pollaris, Sven Seys, Carolina Aznar Lopez, Erik Verbeken, Matthias Tenbusch, Rik Lories, Benoit Nemery, Peter HM Hoet, Jeroen AJ Vanoirbeek
Published 2017-06-01

Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques.

by Matthias Tenbusch, Ralf Ignatius, Godwin Nchinda, Christine Trumpfheller, Andres M Salazar, Katharina Töpfer, Ulrike Sauermann, Ralf Wagner, Drew Hannaman, Klara Tenner-Racz, Paul Racz, Christiane Stahl-Hennig, Klaus Uberla
Published 2012-01-01

SARS-CoV-2-Seronegative Subjects Target CTL Epitopes in the SARS-CoV-2 Nucleoprotein Cross-Reactive to Common Cold Coronaviruses

by Katja G. Schmidt, Krystelle Nganou-Makamdop, Matthias Tenbusch, Boutaina El Kenz, Boutaina El Kenz, Clara Maier, Dennis Lapuente, Klaus Überla, Bernd Spriewald, Silke Bergmann, Ellen G. Harrer, Thomas Harrer
Published 2021-04-01

Replication of Influenza A Virus in Secondary Lymphatic Tissue Contributes to Innate Immune Activation

by Sarah-Kim Friedrich, Rosa Schmitz, Michael Bergerhausen, Judith Lang, Vikas Duhan, Cornelia Hardt, Matthias Tenbusch, Marco Prinz, Kenichi Asano, Hilal Bhat, Thamer A. Hamdan, Philipp Alexander Lang, Karl Sebastian Lang
Published 2021-05-01

A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants

by Niklas Vesper, Niklas Vesper, Yaneth Ortiz, Yaneth Ortiz, Frauke Bartels-Burgahn, Frauke Bartels-Burgahn, Jianying Yang, Jianying Yang, Kathrin de la Rosa, Matthias Tenbusch, Sebastian Schulz, Stephanie Finzel, Hans-Martin Jäck, Hermann Eibel, Hermann Eibel, Reinhard E. Voll, Reinhard E. Voll, Michael Reth, Michael Reth
Published 2021-09-01

Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German...

by Ralf Wagner, David Peterhoff, Stephanie Beileke, Felix Günther, Melanie Berr, Sebastian Einhauser, Anja Schütz, Hans Helmut Niller, Philipp Steininger, Antje Knöll, Matthias Tenbusch, Clara Maier, Klaus Korn, Klaus J. Stark, André Gessner, Ralph Burkhardt, Michael Kabesch, Holger Schedl, Helmut Küchenhoff, Annette B. Pfahlberg, Iris M. Heid, Olaf Gefeller, Klaus Überla
Published 2021-06-01

Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

by Vugar Azizov, Katharina Dietel, Franziska Steffen, Kerstin Dürholz, Julia Meidenbauer, Sébastien Lucas, Michael Frech, Yasunori Omata, Narges Tajik, Lisa Knipfer, Anne Kolenbrander, Silvia Seubert, Dennis Lapuente, Maria V. Sokolova, Jörg Hofmann, Matthias Tenbusch, Andreas Ramming, Ulrike Steffen, Falk Nimmerjahn, Ralf Linker, Stefan Wirtz, Martin Herrmann, Vladimir Temchura, Kerstin Sarter, Georg Schett, Mario M. Zaiss
Published 2020-04-01

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

by Paul David, Malgorzata Drabczyk-Pluta, Eva Pastille, Torben Knuschke, Tanja Werner, Nadine Honke, Dominik A Megger, Ilseyar Akhmetzyanova, Namir Shaabani, Annette Eyking-Singer, Elke Cario, Olivia Kershaw, Achim D Gruber, Matthias Tenbusch, Kirsten K Dietze, Mirko Trilling, Jia Liu, Dirk Schadendorf, Hendrik Streeck, Karl S Lang, Youhua Xie, Lisa Zimmer, Barbara Sitek, Annette Paschen, Astrid M Westendorf, Ulf Dittmer, Gennadiy Zelinskyy
Published 2020-03-01

Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion

by David Simon, Koray Tascilar, Gerhard Krönke, Arnd Kleyer, Mario M. Zaiss, Franz Heppt, Christine Meder, Raja Atreya, Entcho Klenske, Peter Dietrich, Abdullah Abdullah, Thorsten Kliem, Giulia Corte, Harriet Morf, Moritz Leppkes, Andreas E. Kremer, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Clara Maier, Axel J. Hueber, Karin Manger, Bernhard Manger, Carola Berking, Matthias Tenbusch, Klaus Überla, Michael Sticherling, Markus F. Neurath, Georg Schett
Published 2020-07-01

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

by Alan Bénard, Anne Jacobsen, Maximilian Brunner, Christian Krautz, Bettina Klösch, Izabela Swierzy, Elisabeth Naschberger, Malgorzata J. Podolska, Dina Kouhestani, Paul David, Torsten Birkholz, Ixchel Castellanos, Denis Trufa, Horia Sirbu, Marcel Vetter, Andreas E. Kremer, Kai Hildner, Andreas Hecker, Fabian Edinger, Matthias Tenbusch, Petra Mühl-Zürbes, Alexander Steinkasserer, Enrico Richter, Hendrik Streeck, Marc M. Berger, Thorsten Brenner, Markus A. Weigand, Filip K. Swirski, Georg Schett, Robert Grützmann, Georg F. Weber
Published 2021-02-01