The Potential of OMICs Technologies for the Treatment of Immune-Mediated Inflammatory Diseases

by Charles Gwellem Anchang, Cong Xu, Maria Gabriella Raimondo, Raja Atreya, Andreas Maier, Georg Schett, Vasily Zaburdaev, Simon Rauber, Andreas Ramming
Published 2021-07-01

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

by Debomita Chakraborty, Barbora Šumová, Tatjana Mallano, Chih-Wei Chen, Alfiya Distler, Christina Bergmann, Ingo Ludolph, Raymund E. Horch, Kolja Gelse, Andreas Ramming, Oliver Distler, Georg Schett, Ladislav Šenolt, Jörg H. W. Distler
Published 2017-10-01

Long-term effectiveness, safety and immunogenicity of the biosimilar SB2 in inflammatory bowel disease patients after switching from originator infliximab

by Sarah Fischer, Sarah Cohnen, Entcho Klenske, Heike Schmitt, Francesco Vitali, Simon Hirschmann, Andreas Ramming, Sebastian Zundler, Timo Rath, Sabine Krebs, Frank Dörje, Wolfgang Uter, Daniel Nagore, Sebastian Meyer, Markus F. Neurath, Raja Atreya
Published 2021-01-01

Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice

by Yasunori Omata, Michael Frech, Tatjana Primbs, Sébastien Lucas, Darja Andreev, Carina Scholtysek, Kerstin Sarter, Markus Kindermann, Nataliya Yeremenko, Dominique L. Baeten, Nico Andreas, Thomas Kamradt, Aline Bozec, Andreas Ramming, Gerhard Krönke, Stefan Wirtz, Georg Schett, Mario M. Zaiss
Published 2018-07-01

ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure

by Anja Schulz-Kuhnt, Vicky Greif, Kai Hildner, Lisa Knipfer, Michael Döbrönti, Sabine Zirlik, Florian Fuchs, Raja Atreya, Sebastian Zundler, Rocío López-Posadas, Clemens Neufert, Andreas Ramming, Alexander Kiefer, Anika Grüneboom, Erwin Strasser, Stefan Wirtz, Markus F. Neurath, Imke Atreya
Published 2020-05-01

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

by Ariella Zehender, Jingang Huang, Andrea-Hermina Györfi, Alexandru-Emil Matei, Thuong Trinh-Minh, Xiaohan Xu, Yi-Nan Li, Chih-Wei Chen, Jianping Lin, Clara Dees, Christian Beyer, Kolja Gelse, Zhong-Yin Zhang, Christina Bergmann, Andreas Ramming, Walter Birchmeier, Oliver Distler, Georg Schett, Jörg H. W. Distler
Published 2018-08-01

TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

by Ariella Zehender, Yi-Nan Li, Neng-Yu Lin, Adrian Stefanica, Julian Nüchel, Chih-Wei Chen, Hsiao-Han Hsu, Honglin Zhu, Xiao Ding, Jingang Huang, Lichong Shen, Andrea-Hermina Györfi, Alina Soare, Simon Rauber, Christina Bergmann, Andreas Ramming, Markus Plomann, Beate Eckes, Georg Schett, Jörg H. W. Distler
Published 2021-07-01

Accuracy, patient-perceived usability, and acceptance of two symptom checkers (Ada and Rheport) in rheumatology: interim results from a randomized controlled crossover trial

by Johannes Knitza, Jacob Mohn, Christina Bergmann, Eleni Kampylafka, Melanie Hagen, Daniela Bohr, Harriet Morf, Elizabeth Araujo, Matthias Englbrecht, David Simon, Arnd Kleyer, Timo Meinderink, Wolfgang Vorbrüggen, Cay Benedikt von der Decken, Stefan Kleinert, Andreas Ramming, Jörg H. W. Distler, Nicolas Vuillerme, Achim Fricker, Peter Bartz-Bazzanella, Georg Schett, Axel J. Hueber, Martin Welcker
Published 2021-04-01

Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

by Vugar Azizov, Katharina Dietel, Franziska Steffen, Kerstin Dürholz, Julia Meidenbauer, Sébastien Lucas, Michael Frech, Yasunori Omata, Narges Tajik, Lisa Knipfer, Anne Kolenbrander, Silvia Seubert, Dennis Lapuente, Maria V. Sokolova, Jörg Hofmann, Matthias Tenbusch, Andreas Ramming, Ulrike Steffen, Falk Nimmerjahn, Ralf Linker, Stefan Wirtz, Martin Herrmann, Vladimir Temchura, Kerstin Sarter, Georg Schett, Mario M. Zaiss
Published 2020-04-01

Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion

by David Simon, Koray Tascilar, Gerhard Krönke, Arnd Kleyer, Mario M. Zaiss, Franz Heppt, Christine Meder, Raja Atreya, Entcho Klenske, Peter Dietrich, Abdullah Abdullah, Thorsten Kliem, Giulia Corte, Harriet Morf, Moritz Leppkes, Andreas E. Kremer, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Clara Maier, Axel J. Hueber, Karin Manger, Bernhard Manger, Carola Berking, Matthias Tenbusch, Klaus Überla, Michael Sticherling, Markus F. Neurath, Georg Schett
Published 2020-07-01