Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
Abstract Background Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary site...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12920-019-0551-2 |