A Cross-Reactive Human Single-Chain Antibody for Detection of Major Fish Allergens, Parvalbumins, and Identification of a Major IgE-Binding Epitope.

A Cross-Reactive Human Single-Chain Antibody for Detection of Major Fish Allergens, Parvalbumins, and Identification of a Major IgE-Binding Epitope.

Fish allergy is associated with moderate to severe IgE-mediated reactions to the calcium binding parvalbumins present in fish muscle. Allergy to multiple fish species is caused by parvalbumin-specific cross-reactive IgE recognizing conserved epitopes. In this study, we aimed to produce cross-reactiv...

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Bibliographic Details
Main Authors: Merima Bublin, Maria Kostadinova, Julian E Fuchs, Daniela Ackerbauer, Adolfo H Moraes, Fabio C L Almeida, Nina Lengger, Christine Hafner, Christof Ebner, Christian Radauer, Klaus R Liedl, Ana Paula Valente, Heimo Breiteneder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4651496?pdf=render

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http://europepmc.org/articles/PMC4651496?pdf=render

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