Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles

Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles

Severe burn injury causes local and systemic immune responses that can persist up to months, and can lead to systemic inflammatory response syndrome, organ damage and long-term sequalae such as hypertrophic scarring. To prevent these pathological conditions, a better understanding of the underlying...

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Bibliographic Details
Main Authors: Patrick P. G. Mulder, Marcel Vlig, Bouke K. H. L. Boekema, Matthea M. Stoop, Anouk Pijpe, Paul P. M. van Zuijlen, Evelien de Jong, Bram van Cranenbroek, Irma Joosten, Hans J. P. M. Koenen, Magda M. W. Ulrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
immune response
neutrophils
monocytes
lymphocytes
systemic
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.621222/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.621222/full

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