Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy.

by Jorieke H Peters, Luuk B Hilbrands, Hans J P M Koenen, Irma Joosten
Published 2008-01-01

Metabolic Pathways Involved in Regulatory T Cell Functionality

by Rosalie W. M. Kempkes, Irma Joosten, Hans J. P. M. Koenen, Xuehui He
Published 2019-12-01

An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro

by Paulo C. M. Urbano, Hans J. P. M. Koenen, Irma Joosten, Xuehui He, Xuehui He
Published 2018-03-01

Immunological monitoring of renal transplant recipients to predict acute allograft rejection following the discontinuation of tacrolimus.

by Ellen Kreijveld, Hans J P M Koenen, Bram van Cranenbroek, Esther van Rijssen, Irma Joosten, Luuk B Hilbrands
Published 2008-01-01

Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation.

by Jorieke H Peters, Frank W Preijers, Rob Woestenenk, Luuk B Hilbrands, Hans J P M Koenen, Irma Joosten
Published 2008-01-01

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells.

by Xuehui He, Sija Landman, Stijn C G Bauland, Juliette van den Dolder, Hans J P M Koenen, Irma Joosten
Published 2016-01-01

Immune responses to azacytidine in animal models of inflammatory disorders: a systematic review

by Sija Landman, Chiel van der Horst, Piet E. J. van Erp, Irma Joosten, Rob de Vries, Hans J. P. M. Koenen
Published 2021-01-01

Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy.

by Elena G Kamburova, Hans J P M Koenen, Martijn W F van den Hoogen, Marije C Baas, Irma Joosten, Luuk B Hilbrands
Published 2014-01-01

COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients

by Matthijs Kox, Tim Frenzel, Jeroen Schouten, Frank L. van de Veerdonk, Hans J. P. M. Koenen, Peter Pickkers, , on behalf of the RCI-COVID-19 study group
Published 2020-05-01

TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression

by Paulo C. M. Urbano, Xuehui He, Bennie van Heeswijk, Omar P. S. Filho, Henk Tijssen, Ruben L. Smeets, Irma Joosten, Hans J. P. M. Koenen
Published 2020-01-01

DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4+CD25high FOXP3+ Regulatory T Cells but Does Not Affect Their Suppressive Capacity

by Sija Landman, Marjan Cruijsen, Paulo C. M. Urbano, Gerwin Huls, Piet E. J. van Erp, Esther van Rijssen, Irma Joosten, Hans J. P. M. Koenen
Published 2018-01-01

Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment.

by Ai-Leng Khoo, Hans J P M Koenen, Louis Y A Chai, Fred C G J Sweep, Mihai G Netea, André J A M van der Ven, Irma Joosten
Published 2012-01-01

Clinical, laboratory, and genetic markers for the development or presence of psoriatic arthritis in psoriasis patients: a systematic review

by Michelle L. M. Mulder, Tamara W. van Hal, Mark H. Wenink, Hans J. P. M. Koenen, Frank H. J. van den Hoogen, Elke M. G. J. de Jong, Juul M. P. A. van den Reek, Johanna E. Vriezekolk
Published 2021-06-01

Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells.

by Vivian L de Oliveira, Romy R M C Keijsers, Peter C M van de Kerkhof, Marieke M B Seyger, Esther Fasse, Lars Svensson, Markus Latta, Hanne Norsgaard, Tord Labuda, Pieter Hupkens, Piet E J van Erp, Irma Joosten, Hans J P M Koenen
Published 2012-01-01

Increased presence of FOXP3+ regulatory T cells in inflamed muscle of patients with active juvenile dermatomyositis compared to peripheral blood.

by Yvonne Vercoulen, Felicitas Bellutti Enders, Jenny Meerding, Maud Plantinga, Elisabeth F Elst, Hemlata Varsani, Christa van Schieveen, Mette H Bakker, Mark Klein, Rianne C Scholman, Wim Spliet, Valeria Ricotti, Hans J P M Koenen, Roel A de Weger, Lucy R Wedderburn, Annet van Royen-Kerkhof, Berent J Prakken
Published 2014-01-01

IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

by Jelle J Lindenberg, Dinja Oosterhoff, Claudia C Sombroek, Sinéad M Lougheed, Erik Hooijberg, Anita G M Stam, Saskia J A M Santegoets, Henk J Tijssen, Jan Buter, Herbert M Pinedo, Alfons J M van den Eertwegh, Rik J Scheper, Hans J P M Koenen, Rieneke van de Ven, Tanja D de Gruijl
Published 2013-01-01

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

by Wouter A. van der Heijden, Lisa Van de Wijer, Farid Keramati, Wim Trypsteen, Sofie Rutsaert, Rob ter Horst, Martin Jaeger, Hans J.P.M. Koenen, Hendrik G. Stunnenberg, Irma Joosten, Paul E. Verweij, Jan van Lunzen, Charles A. Dinarello, Leo A.B. Joosten, Linos Vandekerckhove, Mihai G. Netea, André J.A.M. van der Ven, Quirijn de Mast
Published 2021-04-01

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytome...

by Lisa Van de Wijer, Wouter A. van der Heijden, Rob ter Horst, Martin Jaeger, Wim Trypsteen, Sofie Rutsaert, Bram van Cranenbroek, Esther van Rijssen, Irma Joosten, Leo Joosten, Linos Vandekerckhove, Till Schoofs, Jan van Lunzen, Mihai G. Netea, Mihai G. Netea, Hans J.P.M. Koenen, André J.A.M. van der Ven, Quirijn de Mast
Published 2021-04-01

Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles

by Patrick P. G. Mulder, Patrick P. G. Mulder, Marcel Vlig, Bouke K. H. L. Boekema, Matthea M. Stoop, Anouk Pijpe, Paul P. M. van Zuijlen, Paul P. M. van Zuijlen, Paul P. M. van Zuijlen, Paul P. M. van Zuijlen, Evelien de Jong, Evelien de Jong, Bram van Cranenbroek, Irma Joosten, Hans J. P. M. Koenen, Magda M. W. Ulrich, Magda M. W. Ulrich
Published 2021-01-01

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

by Raúl Aguirre-Gamboa, Niek de Klein, Jennifer di Tommaso, Annique Claringbould, Monique GP van der Wijst, Dylan de Vries, Harm Brugge, Roy Oelen, Urmo Võsa, Maria M. Zorro, Xiaojin Chu, Olivier B. Bakker, Zuzanna Borek, Isis Ricaño-Ponce, Patrick Deelen, Cheng-Jiang Xu, Morris Swertz, Iris Jonkers, Sebo Withoff, Irma Joosten, Serena Sanna, Vinod Kumar, Hans J. P. M. Koenen, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, BIOS Consortium, Lude Franke, Yang Li
Published 2020-06-01