Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

by Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, BIOS Consortium, Harm-Jan Westra, Yang Li, Cisca Wijmenga, Serena Sanna
Published 2020-10-01

Correction for both common and rare cell types in blood is important to identify genes that correlate with age

by Damiano Pellegrino-Coppola, Annique Claringbould, Maartje Stutvoet, BIOS Consortium, Dorret I. Boomsma, M. Arfan Ikram, P. Eline Slagboom, Harm-Jan Westra, Lude Franke
Published 2021-03-01

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

by Jeroen van Rooij, Pooja R. Mandaviya, Annique Claringbould, Janine F. Felix, Jenny van Dongen, Rick Jansen, Lude Franke, BIOS consortium, Peter A. C. ’t Hoen, Bas Heijmans, Joyce B. J. van Meurs
Published 2019-11-01

A SNP panel for identification of DNA and RNA specimens

by Soheil Yousefi, Tooba Abbassi-Daloii, Thirsa Kraaijenbrink, Martijn Vermaat, Hailiang Mei, Peter van ‘t Hof, Maarten van Iterson, Daria V. Zhernakova, Annique Claringbould, Lude Franke, Leen M. ‘t Hart, Roderick C. Slieker, Amber van der Heijden, Peter de Knijff, BIOS consortium, Peter A. C. ’t Hoen
Published 2018-01-01

Gender differences in the mental health impact of the COVID-19 lockdown: Longitudinal evidence from the Netherlands

by A. Vloo, R.J.M. Alessie, J.O. Mierau, Marike H. Boezen, Jochen O. Mierau, Lude Franke, Jackie Dekens, Patrick Deelen, Pauline Lanting, Judith M. Vonk, Ilja Nolte, Anil P.S. Ori, Annique Claringbould, Floranne Boulogne, Marjolein X.L. Dijkema, Henry H. Wiersma, Robert Warmerdam, Soesma A. Jankipersadsing
Published 2021-09-01

Association between socioeconomic status and self-reported, tested and diagnosed COVID-19 status during the first wave in the Northern Netherlands: a general population-based cohor...

by Jochen Mierau, Pauline Lanting, Patrick Deelen, Robert Warmerdam, Floranne Boulogne, Annique Claringbould, Lude Franke, Yinjie Zhu, Ming-Jie Duan, Hermien H. Dijk, Roel D. Freriks, Louise H. Dekker, Jochen O. Mierau, Marike Boezen, Jackie Dekens, Judith Vonk, Ilja Nolte, Anil Ori, Marjolein Dijkema, Henry Wiersma, Soesma Medema Jankipersadsing
Published 2021-03-01

Genome-wide identification of directed gene networks using large-scale population genomics data

by René Luijk, Koen F. Dekkers, Maarten van Iterson, Wibowo Arindrarto, Annique Claringbould, Paul Hop, Dorret I. Boomsma, Cornelia M. van Duijn, Marleen M. J. van Greevenbroek, Jan H. Veldink, Cisca Wijmenga, Lude Franke, Peter A. C. ’t Hoen, Rick Jansen, Joyce van Meurs, Hailiang Mei, P. Eline Slagboom, Bastiaan T. Heijmans, Erik W. van Zwet, BIOS (Biobank-based Integrative Omics Study) Consortium
Published 2018-08-01

Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort

by Sandra Brouwer, Ute Bültmann, Jochen Mierau, Johanna C Herkert, Katherine Mc Intyre, Pauline Lanting, Patrick Deelen, Henry H Wiersma, Anil P S Ori, Soesma A Jankipersadsing, Robert Warmerdam, Irene van Blokland, Floranne Boulogne, Marjolein X L Dijkema, Annique Claringbould, Olivier Bakker, Esteban A Lopera Maya, Sijmen A Reijneveld, Elianne Zijlstra, Morris A Swertz, Raun van Ooijen, Viola Angelini, Louise H Dekker, Anna Sijtsma, Sicco A Scherjon, Jackie A M Dekens, Lude Franke
Published 2021-03-01

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

by Adriaan van der Graaf, Maria M. Zorro, Annique Claringbould, Urmo Võsa, Urmo Võsa, Raúl Aguirre-Gamboa, Chan Li, Chan Li, Joram Mooiweer, Isis Ricaño-Ponce, Zuzanna Borek, Zuzanna Borek, Frits Koning, Yvonne Kooy-Winkelaar, Ludvig M. Sollid, Shuo-Wang Qiao, Vinod Kumar, Vinod Kumar, Yang Li, Yang Li, Yang Li, Lude Franke, Sebo Withoff, Cisca Wijmenga, Cisca Wijmenga, Serena Sanna, Serena Sanna, Iris Jonkers, Iris Jonkers, BIOS Consortium
Published 2021-01-01

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

by Raúl Aguirre-Gamboa, Niek de Klein, Jennifer di Tommaso, Annique Claringbould, Monique GP van der Wijst, Dylan de Vries, Harm Brugge, Roy Oelen, Urmo Võsa, Maria M. Zorro, Xiaojin Chu, Olivier B. Bakker, Zuzanna Borek, Isis Ricaño-Ponce, Patrick Deelen, Cheng-Jiang Xu, Morris Swertz, Iris Jonkers, Sebo Withoff, Irma Joosten, Serena Sanna, Vinod Kumar, Hans J. P. M. Koenen, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, BIOS Consortium, Lude Franke, Yang Li
Published 2020-06-01

Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility.

by Irene V van Blokland, Pauline Lanting, Anil P S Ori, Judith M Vonk, Robert C A Warmerdam, Johanna C Herkert, Floranne Boulogne, Annique Claringbould, Esteban A Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Lifelines COVID-19 cohort study, COVID-19 Host Genetics Initiative, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T Cirulli, Kelly M Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M Ramirez, Yan Wei Lim, James T Lu, Nicole L Washington, Eco J C de Geus, Patrick Deelen, H Marike Boezen, Lude H Franke
Published 2021-01-01

Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility

by Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert C. A. Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Lifelines COVID-19 cohort study, The COVID-19 Host Genetics Initiative, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T. Cirulli, Kelly M. Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M. Ramirez, Yan Wei Lim, James T. Lu, Nicole L. Washington, Eco J. C. de Geus, Patrick Deelen, H. Marike Boezen, Lude H. Franke
Published 2021-01-01