Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells

Abstract Tumor microenvironment favors tumor cells to promote their growth and metastasis such as migration, invasion, and angiogenesis. IL-1β, one of the inflammatory cytokines released from myeloid cells in tumor microenvironment, plays an important role in development and progress of tumor. The a...

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Bibliographic Details
Main Authors: Hye Eun Lee, Jin Young Lee, Gabsik Yang, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48794-x