A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS

A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS

Cell migration through the brain parenchyma underpins neurogenesis and glioblastoma (GBM) development. Since GBM cells and neuroblasts use the same migratory routes, mechanisms underlying migration during neurogenesis and brain cancer pathogenesis may be similar. Here, we identify a common pathway c...

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Bibliographic Details
Main Authors: Valeria Amodeo, Deli A, Joanne Betts, Stefano Bartesaghi, Ying Zhang, Angela Richard-Londt, Matthew Ellis, Rozita Roshani, Mikaella Vouri, Sara Galavotti, Sarah Oberndorfer, Ana Paula Leite, Alan Mackay, Aikaterini Lampada, Eva Wessel Stratford, Ningning Li, David Dinsdale, David Grimwade, Chris Jones, Pierluigi Nicotera, David Michod, Sebastian Brandner, Paolo Salomoni
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
PML
neurogenesis
cell migration
glioblastoma
Slit
Polycomb
nuclear lamina
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717308616

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http://www.sciencedirect.com/science/article/pii/S2211124717308616

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