Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

Abstract Objectives T cells have an essential role in the antiviral defence. Public T‐cell receptor (TCR) clonotypes are expanded in a substantial proportion of COVID‐19 patients. We set out to exploit their potential use as read‐out for COVID‐19 T‐cell immune responses. Methods We searched for COVI...

Full description

Bibliographic Details
Main Authors: Donjete Simnica, Christoph Schultheiß, Malte Mohme, Lisa Paschold, Edith Willscher, Antonia Fitzek, Klaus Püschel, Jakob Matschke, Sandra Ciesek, Daniel G Sedding, Yu Zhao, Nicola Gagliani, Yacine Maringer, Juliane S Walz, Janna Heide, Julian Schulze‐zur‐Wiesch, Mascha Binder
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
COVID‐19
public T‐cell receptors
risk cohort
T‐cell repertoire
Online Access:https://doi.org/10.1002/cti2.1340

Internet

https://doi.org/10.1002/cti2.1340

Similar Items