Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas.

Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas.

Malignant gliomas are highly infiltrative and invasive tumors, which precludes the few treatment options available. Therefore, there is an urgent need to elucidate the molecular mechanisms underlying gliomas aggressive phenotype and poor prognosis. The Raf Kinase Inhibitory protein (RKIP), besides r...

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Main Authors: Olga Martinho, Sara Granja, Teresa Jaraquemada, Cláudia Caeiro, Vera Miranda-Gonçalves, Mrinalini Honavar, Paulo Costa, Margarida Damasceno, Marsha R Rosner, José M Lopes, Rui M Reis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22292035/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22292035/?tool=EBI

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