Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

Background: Cerebrospinal fluid (CSF) neurofilament light chain protein (NFL) is a sensitive marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS dysfunction injury that is common in untreated HIV infection. However, an important limitation is the requirement for...

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Bibliographic Details
Main Authors: Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:EBioMedicine
Subjects:
HIV
Cerebrospinal Fluid
CSF
Plasma
Neurofilament Light Chain
NFL
Biomarker
Central Nervous System
CNS
HIV Associated Dementia
HAD
Antiretroviral Treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641530219X

Internet

http://www.sciencedirect.com/science/article/pii/S235239641530219X

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