Metabolomics Insights of the Immunomodulatory Activities of Phlorizin and Phloretin on Human THP-1 Macrophages

Metabolomics Insights of the Immunomodulatory Activities of Phlorizin and Phloretin on Human THP-1 Macrophages

Dihydrochalcones, phlorizin (PZ) and its aglycone phloretin (PT), have evidenced immunomodulatory effects through several mechanisms. However, the differential metabolic signatures that lead to these properties are largely unknown. Since macrophages play an important role in the immune response, our...

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Bibliographic Details
Main Authors: Noelia Cambeiro-Pérez, Xiana González-Gómez, Carmen González-Barreiro, María Rosa Pérez-Gregorio, Iva Fernandes, Nuno Mateus, Victor de Freitas, Borja Sánchez, Elena Martínez-Carballo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
untargeted metabolomics
THP-1 macrophages
phloretin
phlorizin
immunomodulation
Online Access:https://www.mdpi.com/1420-3049/26/4/787

Internet

https://www.mdpi.com/1420-3049/26/4/787

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