Partial restoration of immune response in Hepatitis C patients after viral clearance by direct-acting antiviral therapy.

<h4>Background & aims</h4>HCV CD4+ and CD8+ specific T cells responses are functionally impaired during chronic hepatitis C infection. DAAs therapies eradicate HCV infection in more than 95% of treated patients. However, the impact of HCV elimination on immune responses remain contro...

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Bibliographic Details
Main Authors: Meritxell Llorens-Revull, Maria Isabel Costafreda, Angie Rico, Mercedes Guerrero-Murillo, Maria Eugenia Soria, Sofía Píriz-Ruzo, Elena Vargas-Accarino, Pablo Gabriel-Medina, Francisco Rodríguez-Frías, Mar Riveiro-Barciela, Celia Perales, Josep Quer, Silvia Sauleda, Juan Ignacio Esteban, Marta Bes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0254243