DNA repair pathway activation features in follicular and papillary thyroid tumors, interrogated using 95 experimental RNA sequencing profiles

DNA repair pathway activation features in follicular and papillary thyroid tumors, interrogated using 95 experimental RNA sequencing profiles

DNA repair can prevent mutations and cancer development, but it can also restore damaged tumor cells after chemo and radiation therapy. We performed RNA sequencing on 95 human pathological thyroid biosamples including 17 follicular adenomas, 23 follicular cancers, 3 medullar cancers, 51 papillary ca...

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Bibliographic Details
Main Authors: Uliana Vladimirova, Pavel Rumiantsev, Marianna Zolotovskaia, Eugene Albert, Aleksander Abrosimov, Konstantin Slashchuk, Petr Nikiforovich, Olga Chukhacheva, Nurshat Gaifullin, Maria Suntsova, Galina Zakharova, Alexander Glusker, Daniil Nikitin, Andrew Garazha, Xinmin Li, Dmitriy Kamashev, Alexei Drobyshev, Irina Kochergina-Nikitskaya, Maxim Sorokin, Anton Buzdin
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Heliyon
Subjects:
DNA repair
Follicular thyroid adenoma
RNA sequencing
Thyroid cancer
Personalized medicine
Molecular biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021005132

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http://www.sciencedirect.com/science/article/pii/S2405844021005132

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