The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection.

The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection.

Innate immunity is regulated by cholinergic signalling through nicotinic acetylcholine receptors. We show here that signalling through the M3 muscarinic acetylcholine receptor (M3R) plays an important role in adaptive immunity to both Nippostrongylus brasiliensis and Salmonella enterica serovar Typh...

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Bibliographic Details
Main Authors: Matthew Darby, Corinna Schnoeller, Alykhan Vira, Fiona Jane Culley, Saeeda Bobat, Erin Logan, Frank Kirstein, Jürgen Wess, Adam F Cunningham, Frank Brombacher, Murray E Selkirk, William G C Horsnell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004636

Internet

https://doi.org/10.1371/journal.ppat.1004636

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