Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic

Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic

Blood microbiome is important to investigate microbial-host interactions and the effects on systemic immune perturbations. However, this effort has met with major challenges due to low microbial biomass and background artifacts. In the current study, microbial 16S DNA sequencing was applied to analy...

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Bibliographic Details
Main Authors: Zhenwu Luo, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Min Li, Quan-Zhen Li, Lei Huang, Betty P. Tsao, Diane L. Kamen, Jim C. Oates, Zihai Li, Gary S. Gilkeson, Wei Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
plasma microbiome
quality-filtering strategies
contaminations and artifacts
pathogenic bacteria
microbiome-host interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.613268/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2020.613268/full

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