Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir

A significant proportion of COVID-19 patients will progress to critical illness requiring invasive mechanical ventilation. This accentuates the need for a therapy that can reduce the severity of COVID-19. Clinical trials have shown the effectiveness of remdesivir in shortening recovery time and decr...

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Bibliographic Details
Main Authors: Yi-Hao Chan, Barnaby E. Young, Siew-Wai Fong, Ying Ding, Yun Shan Goh, Rhonda Sin-Ling Chee, Seow-Yen Tan, Shirin Kalimuddin, Paul A. Tambyah, Yee-Sin Leo, Lisa F. P. Ng, David Chien Lye, Laurent Renia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680188/full