Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets.

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets.

Food intake and body weight are controlled by a variety of central and peripheral factors, but the exact mechanisms behind these processes are still not fully understood. Here we show that that macrophage inhibitory cytokine-1 (MIC-1/GDF15), known to have anorexigenic effects particularly in cancer,...

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Bibliographic Details
Main Authors: Laurence Macia, Vicky Wang-Wei Tsai, Amy D Nguyen, Heiko Johnen, Tamara Kuffner, Yan-Chuan Shi, Shu Lin, Herbert Herzog, David A Brown, Samuel N Breit, Amanda Sainsbury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325923?pdf=render

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http://europepmc.org/articles/PMC3325923?pdf=render

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