Precancerous stem cells have the potential for both benign and malignant differentiation.

Precancerous stem cells have the potential for both benign and malignant differentiation.

Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors-namely, precancerous stem cells (pCSCs) -have not been characterized. Here we experimentally define the pCSCs that have the potential for both benign and malignant differentiation, depending on...

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Bibliographic Details
Main Authors: Li Chen, Rulong Shen, Yin Ye, Xin-An Pu, Xingluo Liu, Wenrui Duan, Jing Wen, Jason Zimmerer, Ying Wang, Yan Liu, Larry C Lasky, Nyla A Heerema, Danilo Perrotti, Keiko Ozato, Satomi Kuramochi-Miyagawa, Toru Nakano, Allen J Yates, William E Carson, Haifan Lin, Sanford H Barsky, Jian-Xin Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1808425?pdf=render

Internet

http://europepmc.org/articles/PMC1808425?pdf=render

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