An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections.

Neutrophils are classically defined as terminally differentiated, short-lived cells; however, neutrophils can be long-lived with phenotypic plasticity. During inflammation, a subset of neutrophils transdifferentiate into a population called neutrophil-DC hybrids (PMN-DCs) having properties of both n...

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Bibliographic Details
Main Authors: J Scott Fites, Michael Gui, John F Kernien, Paige Negoro, Zeina Dagher, David B Sykes, Jeniel E Nett, Michael K Mansour, Bruce S Klein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5983859?pdf=render