Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome

Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome

Zebrafish represent a valuable model for investigating the molecular and cellular basis of Fragile X syndrome (FXS). Reduced expression of the zebrafish FMR1 orthologous gene, fmr1, causes developmental and behavioural phenotypes related to FXS. Zebrafish homozygous for the hu2787 non-sense mutation...

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Bibliographic Details
Main Authors: Karissa Barthelson, Lachlan Baer, Yang Dong, Melanie Hand, Zac Pujic, Morgan Newman, Geoffrey J. Goodhill, Robert I. Richards, Stephen M. Pederson, Michael Lardelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
fragile X syndrome
zebrafish
transcriptional adaptation
transcriptome analysis
FMR1
chromosome evolution
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.625466/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.625466/full

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