Mechanisms of Resistance to Immunotoxins Containing <i>Pseudomonas</i> Exotoxin A in Cancer Therapy
Immunotoxins are a class of targeted cancer therapeutics in which a toxin such as <i>Pseudomonas</i> exotoxin A (PE) is linked to an antibody or cytokine to direct the toxin to a target on cancer cells. While a variety of PE-based immunotoxins have been developed and a few have demonstra...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/10/7/979 |