The regulatory genome constrains protein sequence evolution: implications for the search for disease-associated genes
The development of explanatory models of protein sequence evolution has broad implications for our understanding of cellular biology, population history, and disease etiology. Here we analyze the GTEx transcriptome resource to quantify the effect of the transcriptome on protein sequence evolution in...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2020-07-01
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| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/9554.pdf |