Antiproliferative and Apoptosis Triggering Potential of Paclitaxel-Based Targeted-Lipid Nanoparticles with Enhanced Cellular Internalization by Transferrin Receptors—a Study in Leukemia Cells

Antiproliferative and Apoptosis Triggering Potential of Paclitaxel-Based Targeted-Lipid Nanoparticles with Enhanced Cellular Internalization by Transferrin Receptors—a Study in Leukemia Cells

Abstract Leukemia is a typical blood cancer that is characterized by the numerous duplication and proliferation of white blood cells. The main aim of this study was to develop PTX-loaded multifunctional nanoparticles and target to leukemia cells. In this study, transferrin-decorated paclitaxel-loade...

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Bibliographic Details
Main Authors: Yang Dai, Jingcao Huang, Bing Xiang, Huanling Zhu, Chuan He
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:Nanoscale Research Letters
Subjects:
Leukemia
Paclitaxel
Lipid nanoparticles
Apoptosis
Cancer targeting
Transferrin
Online Access:http://link.springer.com/article/10.1186/s11671-018-2688-x

Internet

http://link.springer.com/article/10.1186/s11671-018-2688-x

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