Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

Abstract Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying pathobiology of COVID-19 will support the design of rational treatments targeting the life cycle of the virus and/or the adverse effects (e.g., multi-organ collapse) that are triggered by COVID-19-med...

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Bibliographic Details
Main Authors: Ioannis P. Trougakos, Kimon Stamatelopoulos, Evangelos Terpos, Ourania E. Tsitsilonis, Evmorfia Aivalioti, Dimitrios Paraskevis, Efstathios Kastritis, George N. Pavlakis, Meletios A. Dimopoulos
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Biomedical Science
Subjects:
ACE2
ARDS
COVID-19
SARS-CoV-2
TMPRSS2
Online Access:https://doi.org/10.1186/s12929-020-00703-5

Internet

https://doi.org/10.1186/s12929-020-00703-5

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