CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis

CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis

Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is a coinhibitory checkpoint protein expressed on the surface of T cells. A recent study by our working group revealed that the rs231775 single nucleotide polymorphism (SNP) in the CTLA-4 gene was associated with the survival of patients with seps...

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Bibliographic Details
Main Authors: Caspar Mewes, Benedikt Büttner, José Hinz, Ayelet Alpert, Aron-Frederik Popov, Michael Ghadimi, Tim Beissbarth, Mladen Tzvetkov, Ole Jensen, Julius Runzheimer, Michael Quintel, Shai Shen-Orr, Ingo Bergmann, Ashham Mansur
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Journal of Clinical Medicine
Subjects:
sepsis
CTLA-4
single nucleotide polymorphisms
haplotypes
survival
predictors
Online Access:http://www.mdpi.com/2077-0383/8/1/70

Internet

http://www.mdpi.com/2077-0383/8/1/70

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