α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

The noradrenergic system is proposed to play a prominent role in the pathogenesis of liver fibrosis. While α1- and β-adrenergic receptors (ARs) are suggested to be involved in a multitude of profibrogenic actions, little is known about α2-AR-mediated effects and their expr...

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Bibliographic Details
Main Authors: Ute A. Schwinghammer, Magda M. Melkonyan, Lilit Hunanyan, Roman Tremmel, Ralf Weiskirchen, Erawan Borkham-Kamphorst, Elke Schaeffeler, Torgom Seferyan, Wolfgang Mikulits, Konstantin Yenkoyan, Matthias Schwab, Lusine Danielyan
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
α2-adrenoceptors
norepinephrine
mesedin
hepatic stellate cells
sinusoidal endothelial cells
liver fibrosis
sinusoidal permeability
Online Access:https://www.mdpi.com/2073-4409/9/2/456

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https://www.mdpi.com/2073-4409/9/2/456

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